Women's Health Weekly
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Gene Therapy
Researchers at University of Arkansas publish new data on gene therapy
December 4th, 2008
"Kruppel-like factor 9 (KLF9) is a transcriptional regulator of uterine endometrial cell proliferation, adhesion and differentiation; processes essential for pregnancy success and which are subverted during tumorigenesis. The network of endometrial genes controlled by KLF9 is largely unknown," scientists in the United States report. "Over-expression of KLF9 in the human endometrial cancer cell line HEC-1-A alters cell morphology, proliferative indices, and differentiation, when compared to KLF9 under-expressing HEC-1-A cells. This cell line provides a unique model for identifying KLF9 downstream gene targets and signaling pathways. HEC-1-A sub-lines differing in...
Source: Women's Health Weekly (2008-12-04)
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