Women's Health Weekly
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Breast Cancer
Research from S.C.L. Wludarski and colleagues has provided new data on breast cancer
December 11th, 2008
"HER2 gene amplification or HER2 protein overexpression predicts a more aggressive clinical course in breast cancer, with a worse response to hormonal therapy, and determines eligibility for the use of the anti-HER2 antibody trastuzumab. For these reasons, the diagnostic assays that determine HER2 status in breast carcinoma have become increasingly important," scientists writing in the journal Applied Immunohistochemistry & Molecular Morphology report. "Our goal was to evaluate the concordance, sensitivity, and specificity of a rabbit monoclonal antibody directed to the extracellular domain of the HER2 receptor (SP3) and compare it with fluorescence in situ...
Source: Women's Health Weekly (2008-12-11)
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