Women's Health Weekly
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Breast Cancer
Researchers from Cardiff University report on findings in breast cancer
December 11th, 2008
In this recent report, researchers in Wales conducted a study "To determine the in vitro effects of simultaneously administered LY29400, PD98059, tamoxifen and eicosapentaenoic acid (EPA) on breast cancer cells, and determine their transcutaneous delivery. Growth assays were performed on MCF-7 cells challenged with IC50 and permeated concentrations of PD98059, LY294002 and tamoxifen firstly in isolation then combined." "Permeation studies were performed using PD98059 and LY294002 (singly or simultaneously) in DMSO then fish oil, with enhancers. Immunocytochemical detection of phospho-MAPK, phospho-Akt, total COX-2 and Ki-67 was performed. When applied singly, fluxes of...
Source: Women's Health Weekly (2008-12-11)
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