Breast Cancer

Studies from V. Dilauro and co-researchers update current data on breast cancer

Published in Women's Health Weekly, December 11th, 2008

According to a study from Italy, "Aims and background. Trastuzumab-based therapy has improved survival of women with human epidermal growth factor receptor 2 (HER2)-overexpressing metastatic breast cancer."

"From September 2002 to July 2006, 45 women with metastatic breast cancer HER2 3+, or 2+ and positive for HER2 gene amplification, were enrolled in the study and received a combination therapy with vinorelbine, 25 mg/m(2) weeks I and 2, plus trastuzumab, 4 mg/kg loading dose and then 2 mg/kg weekly, in a three weeks cycle. Eligibility criteria included measurable disease and a baseline ejection fraction 260%. Forty-two percent of the patients were not pretreated,...

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Source: Women's Health Weekly (2008-12-11)

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