Life Sciences

Research from Tufts University, Medical Department in the area of life sciences published

Published in Women's Health Weekly, December 11th, 2008

"Stromal-epithelial interactions mediate mammary gland development and the formation and progression of breast cancer. To study these interactions in vitro, the development of defined three-dimensional (3D) models is essential," scientists in the United States report.

"In the present study, we have successfully developed novel 3D in vitro models that allow the formation of mammary gland structures closely resembling those found in vivo. Cocultures of a human mammary epithelial cell line MCF10A and human mammary fibroblasts obtained from reduction mammoplasties embedded in either a type I collagen or a mixed Matrigel-collagen matrix were carried out for up to 6 weeks....

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Source: Women's Health Weekly (2008-12-11)

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