Women's Health Weekly
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Cancer
New cancer study findings have been reported by M.E. Nolan and colleagues
December 18th, 2008
"The polarity protein complex Par6/atypical protein kinase (aPKC)/Cdc42 regulates polarization processes during epithelial morphogenesis, astrocyte migration, and axon specification. We, as well as others, have shown that this complex is also required for disruption of apical-basal polarity during the oncogene ErbB2-induced transformation and transforming growth factor beta-induced epithelial-mesenchymal transition of mammary epithelial cells," scientists writing in the journal Cancer Research report. "Here, we report that expression of Par6 by itself in mammary epithelia] cells induces epidermal growth factor-independent cell proliferation and development of...
Source: Women's Health Weekly (2008-12-18)
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