Women's Health Weekly
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Cancer
Reports from University of Pittsburgh describe recent advances in cancer
December 18th, 2008
"Quercetin, a ubiquitous bioactive plant flavonoid, has been shown to inhibit. the proliferation of cancer cells and induce the accumulation of hypoxia-inducible factor-1 alpha (HIF-1 alpha) in normoxia. In this study, under hypoxic conditions (1% O-2), we examined the effect of quercetin on the intracellular level of HIF-1 alpha and extracellular level of vascular endothelial growth factor (VEGF) in a variety of human cancer cell lines," scientists writing in the Journal of Cellular Biochemistry report. "Surprisingly, we observed that quercetin suppressed the HIF-1 alpha accumulation during hypoxia in human prostate cancer LNCaP, colon cancer CX-1, and breast...
Source: Women's Health Weekly (2008-12-18)
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