Transdermal Delivery

Scientists at Vanderbilt University target transdermal delivery

Published in Women's Health Weekly, December 25th, 2008

"Statins have been shown to stimulate BMP2 transcription and bone formation. This raises the possibility that they could be useful for enhancing rates of fracture repair," scientists in the United States report.

"Observational Studies in patients treated with oral statins for lipid-lowering have been controversial. The likely reason for their inconsistent effects is that the statin concentration reaching, the periphery Was too low after oral administration to produce a reproducible biologic effect. Thus, We examined the effects of lovastatin (LV) given transdermally in a well-described preclinical model of fracture repair. Effects oil the healing fracture callus were...

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Source: Women's Health Weekly (2008-12-25)

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