Women's Health Weekly
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Cervical Cancer
Research conducted at University of Franche-Comte has updated our knowledge about cervical cancer
December 25th, 2008
"Integration of human papillomavirus (HPV) DNA into the host cell genome is a frequent event in cervical carcinogenesis, even though this phenomenon does not seem to be mandatory for cervical cancer development. Our objective was to describe the load and physical state of HPV type 16 (HPV16) DNA in a series of cervical samples representative of the natural history of cervical cancer," scientists writing in the Journal of Clinical Microbiology report. "We used a combination of three real-time PCR assays targeting E6, E2, and albumin genes to calculate HPV16 load (E6 and albumin) and the E2/E6 ratio as a surrogate of integration. This method was applied to 173...
Source: Women's Health Weekly (2008-12-25)
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