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Women's Health Weekly

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Breast Cancer



New breast cancer study findings recently were published by researchers at Louisiana State University



January 1st, 2009

"Eukaryotic Initiation Factor 4E (eIF4E) plays a crucial role in translation control. High eIF4E increase in tumor specimens independently predicted recurrence by multivariate analysis," investigators in the United States report.

"This prospective trial of node-negative only breast cancer patients was initiated to test the hypothesis that high eIF4E increase predicts cancer recurrence and death, independent of nodal status. The trial was powered to detect a 2.4-fold increase in relative risk for cancer recurrence in 240 node-negative patients on the basis of high versus low eIF4E increase in tumor specimens (type I error = .05, statistical power = .08). eIF4E level was...


Source: Women's Health Weekly (2009-01-01)

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