Women's Health Weekly
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Breast Cancer
New research on breast cancer from University of Dundee summarized
January 1st, 2009
According to a study from Scotland, "A functional polymorphism within MDM2, SNP309 T> G, has been linked to early onset cancer. This study examined clinical associations of breast cancer with SNP309 in a Scottish Caucasian population and investigated additional MDM2 intron 1 polymorphisms." "Intron 1 of MDM2 was PCR amplified and directly sequenced from 299 breast cancer patients and 275 cancer free controls and compared with clinical and pathological parameters. SNP309 was observed, for the control and breast cancer cohorts respectively, at frequencies of: T/T = 44.7% and 39.5%; G/T = 42.2% and 47.2%; G/G = 13.1% and 13.4%, indicating that SNP309 is not a...
Source: Women's Health Weekly (2009-01-01)
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