Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Research from S. Lal and co-researchers yields new findings on breast cancer
January 1st, 2009
"The present study aimed to identify polymorphic genes encoding carbonyl reductases (CBR1, CBR3) and investigate their influence on doxorubicin disposition in Asian breast cancer patients (n = 62). Doxorubicin (60 mg/m(2)) was administered every 3 weeks for four to six cycles and the pharmacokinetic parameters were estimated using non-compartmental analysis (WinNonlin)," researchers in Singapore, Singapore report. "The Mann-Whitney U-test was used to assess genotypic-phenotypic correlations. Five CBR1 (-48G > A, c.219G > C, c.627C > T, c.693G > A, +967G > A) and CBR3 (c.11G > A, c.255C > T, c.279C > T, c.606G > A, c.730G > A) polymorphisms...
Source: Women's Health Weekly (2009-01-01)
|
