Women's Health Weekly
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Breast Cancer
Studies from Y. Katsuno and co-researchers update current data on breast cancer
January 1st, 2009
According to recent research from Tokyo, Japan, "Transforming growth factor (TGF)-beta is known to promote tumor invasion and metastasis. Although bone morphogenetic proteins ( BMPs), members of the TGF-beta family, are expressed in a variety of human carcinoma cell lines, their roles in tumor progression have not been fully clarified." "In this study, we sought to determine the roles of BMPs in the progression of breast cancer bone metastasis using human breast cancer samples and a mouse xenograft model. Immunohistochemical analysis of samples from breast cancer patients as well as a mouse xenograft model of MDA-231-D, highly metastatic human breast cancer cells,...
Source: Women's Health Weekly (2009-01-01)
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