Women's Health Weekly
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Breast Cancer
Study findings from R.E. Ellsworth et al broaden understanding of breast cancer
January 1st, 2009
According to recent research from the United States, "Genomic alterations of the proto-oncogene c-erbB-2 (HER-2/neu) are associated with aggressive behavior and poor prognosis in patients with breast cancer. The variable clinical outcomes seen in patients with similar HER2 status, given similar treatments, suggests that the effects of amplification of HER2 can be influenced by other genetic changes." "To assess the broader genomic implications of structural changes at the HER2 locus, we investigated relationships between genomic instability and HER2 status in patients with invasive breast cancer. HER2 status was determined using the PathVysion (R) assay. DNA was...
Source: Women's Health Weekly (2009-01-01)
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