Women's Health Weekly
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Cancer
Researchers at University of Cambridge have published new data on cancer
January 1st, 2009
According to recent research published in the journal BMC Cancer, "Rearrangement of the short arm of chromosome 8 (8p) is very common in epithelial cancers such as breast cancer. Usually there is an unbalanced translocation breakpoint in 8p12 (29.7 Mb-38.5 Mb) with loss of distal 8p, sometimes with proximal amplification of 8p11-12." "Rearrangements in 8p11-12 have been investigated using high-resolution array CGH, but the first 30 Mb of 8p are less well characterised, although this region contains several proposed tumour suppressor genes. We analysed the whole of 8p by array CGH at tiling-path BAC resolution in 32 breast and six pancreatic cancer cell lines....
Source: Women's Health Weekly (2009-01-01)
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