Gynecology

Studies from K. Kokawa and colleagues reveal new findings on gynecology

Published in Women's Health Weekly, January 8th, 2009

"A phase 1 study to evaluate combined therapy with irinotecan (CPT-11), mitomycin-C (MMC), and 5-fluorouracil (5-FU) was performed in patients with gynecological malignancy, especially non-squamous cell carcitinoma of the uterine cervix. Eligibility, for the study included patients with previously, untreated. chemotherapy-naive cervical and ovarian carcinoma," scientists in Kimiidera, Japan report.

"CPTI I and MMC were administered on days I and 15 by intravenous infusion, while 5-FU was given on days 3 to 7. This regimen was repeated after 5 weeks. Four escalating dose levels were carried out (CPT-11/MMC: 120/5. 120/6, 150/6, and 150/7 mg/m(2): 5-FU 600 mg/m(2) fixed)....

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Source: Women's Health Weekly (2009-01-08)

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