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Women's Health Weekly

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Breast Cancer



Research from A.A. Elmabhouh and co-authors in the area of breast cancer published



January 8th, 2009

"Animal models are useful tools to study etiology, progress, and new treatments of disease and are an approximation of human disease for experimental study. Intracardiac injection of the human estrogen-independent breast cancer cell line MDA-MB-231 in nude mice is a well-characterized animal model of bone metastasis mainly used to study new treatments for late-stage breast cancer," investigators in Edmonton, Canada report.

"According to the published literature, this model should produce radiologically distinguishable bone tumors within 17 days after injection. Mice should develop complications such as cachexia, paraplegia, and morbidity within 28 days and require...


Source: Women's Health Weekly (2009-01-08)

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