Women's Health Weekly
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Breast Cancer
New breast cancer study findings recently were published by researchers at Lund University
January 15th, 2009
"Differential regulation as well as target gene specificity of the two hypoxia-inducible factor (HIF)-alpha subunits HIF-1 alpha and HIF-2 alpha in various tumors and cell lines have been suggested. In breast cancer, the prognostic significance of HIF-1 alpha is not clear-cut and that of HIF-2 alpha is largely unknown," researchers in Malmo, Sweden report. "Using IHC analyses of HIF-1 alpha, HIF-2 alpha, and vascular endothelial growth factor (VEGF) expression in a tissue microarray of invasive breast cancer specimens from 512 patients, we investigated the expression patterns of the 2 HIF-alpha subunits in relation to established clinicopathologic variables, VEGF...
Source: Women's Health Weekly (2009-01-15)
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