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University of Warwick

How chromosomes meet in the dark -- switch that turns on X chromosome matchmaking

Published in Women's Health Weekly, January 15th, 2009

A research group lead by scientists at the University of Warwick has discovered the trigger that pulls together X chromosomes in female cells at a crucial stage of embryo development. Their discovery could also provide new insights into how other similar chromosomes spontaneously recognize each other and are bound together at key parts of analogous cell processes. This is an important mechanism as the binding togetgher of too many of too few of a particular chromosome can cause a number of medical conditions such as Down's Syndrome or Turner's Syndrome.

In our cells most genes are expressed from both types of each chromosome linked gene, but the most notable exception...

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