Women's Health Weekly
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Breast Cancer
Data on breast cancer published by N. Navarrotito and colleagues
January 15th, 2009
"Arachiclonic acid (AA) is a common dietary n-6 polyunsaturated fatty acid that is present in an esterified form in cell membrane phospholipids, and it might be present in the extracellular microenvironment. In particular, AA promotes MAPK activation and mediates the adhesion of MDA-MB-435 breast cancer cells to type IV collagen," scientists writing in the journal Experimental Cell Research report. "However, the signal transduction pathways mediated by AA have not been studied in detail. Our results demonstrate that stimulation of MDA-MB-231 breast cancer cells with AA promotes an increase in the phoshorylation of Src and FAK, as revealed by site-specific...
Source: Women's Health Weekly (2009-01-15)
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