Women's Health Weekly
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Cancer
New cancer research from K. Kikuchi and colleagues discussed
January 15th, 2009
According to recent research published in the journal Cancer Science, "Invadopodia, small protrusions formed at ventral membranes of several types of invasive cancer cells upon contact with the extracellular matrix (ECM), are implicated in cell invasion; however, the relationship between invadopodia formation and cell invasion through the ECM is still unknown. To correlate the formation of membrane protrusions and cell invasion, a three-dimensional (3-D) gel culture system with native collagen type-I matrix overlaid with a thin basement membrane equivalent (Matrigel) was made." "Human breast cancer cell line MDA-MB-231 formed long protrusions in addition to small...
Source: Women's Health Weekly (2009-01-15)
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