Women's Health Weekly
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Angiogenesis
Scientists at Korea University report research in angiogenesis
January 22nd, 2009
"Since calpain 6 is overexpressed in uterine cervical cancer tissue compared to normal tissue, we sought to define the role of calpain 6 during tumorigenesis," scientists writing in the journal Cancer Letters report. "We overexpressed calpain 6 or inhibited calpain 6 in human cervical cancer cells (HeLa cells) and human umbilical vein endothelial cells (HUVECs), and measured cisplatin-mediated apoptosis and VEGF-mediated angiogenesis. The results indicated that calpain 6 supported tumorigenesis by inhibiting apoptosis and facilitating angiogenesis," wrote S.B. Rho and colleagues, Korea University. The researchers concluded: "To our knowledge,...
Source: Women's Health Weekly (2009-01-22)
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