Women's Health Weekly
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Breast Cancer
Research findings from University Hospital update understanding of breast cancer
January 22nd, 2009
"The aim of the study was to evaluate the prognostic ability of the transcriptional profiling of the HER family genes in early breast cancer, as well as to investigate the predictive value of HER2 mRNA expression for adjuvant treatment with paclitaxel. RNA was extracted from 268 formalin-fixed paraffin-embedded (FFPE) tumour tissue samples of high-risk breast cancer patients enrolled in the randomised HE10/97 trial, evaluating the effect of dose-dense anthracycline-based sequential adjuvant chemotherapy with or without paclitaxel," scientists in Rion, Greece report. "The mRNA expression of all four HER family members was assessed by kinetic reverse...
Source: Women's Health Weekly (2009-01-22)
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