Women's Health Weekly
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Breast Cancer
Scientists at St. Louis University, Medical Department target breast cancer
January 22nd, 2009
According to recent research from the United States, "AP-2 alpha, interleukin-4 (ILA), E-cadherin, fibulin I D, p16(INK4 alpha), PTEN, RKIP, and S100A4 are determinants (suppressors, except for S100A4) of cancer cell invasiveness and other traits of cancer progression, which are located upstream of matrix metalloproteinases (MMPs) in cell signaling pathways. We will refer to them as upstream cancer-progression determinants (UCPDs, for brevity)." "MMP-1, MMP-2, MMP-9, MMP-11, MMP-13, MMP-14, MMP-16, and MMP-19 are enhancers of cancer cell invasiveness and other traits of cancer progression, in MDA-MB-231 breast cancer cells. We are interested in pathway links from UCPDs...
Source: Women's Health Weekly (2009-01-22)
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