Women's Health Weekly
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Breast Cancer
Studies from China Pharmaceutical University reveal new findings on breast cancer
January 22nd, 2009
According to recent research from Nanjing, People's Republic of China, "Cancer cell invasion is one of the crucial events in local spreading, growth, and metastasis of tumors. The present study investigated the antiinvasive and antimetastatic action of gambogic acid (GA) in MDA-MB-435 human breast carcinoma cells." "GA caused a concentration-dependent suppression of cell invasion through Matrigel and significantly inhibited lung metastases of the cells transplanted in vivo. The potent effects of GA have been attributed to its ability to reduce the expression of matrix metalloproteinases (MMP) 2 and 9 in vitro and in vivo both at the protein and mRNA levels, which were...
Source: Women's Health Weekly (2009-01-22)
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