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Women's Health Weekly

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Breast Cancer



Researchers from University of Siena publish findings in breast cancer



January 29th, 2009

"The purpose of this prospective observational study was to analyze the role of Mib-1 immunostaining as a proliferation index in breast cancer. Correlations between Mib-1 expression and clinico-pathological characteristics as well as its prognostic value have been studied in a series of 432 node negative breast cancers," investigators in Siena, Italy report.

"Mib-1 expression was evaluated by immunohistochemistry. Turner sections from highly cellular invasive areas of cancer were stained by monoclonal antibody Mib-1 (Dako) and cells whose nuclei stained positive were counted in 10 randomly chosen HPFs and expressed as percentages of all epithelial cells. A minimum of...


Source: Women's Health Weekly (2009-01-29)

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