Women's Health Weekly
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Breast Cancer
Research conducted at Y. Gao and co-authors has provided new information about breast cancer
February 5th, 2009
According to recent research from Shanghai, People's Republic of China, "Docetaxel is one of the most promising chemotherapeutic agents for the treatment of metastatic breast cancer, but it shows tearful side effects. We hypothesized that a novel targeted nanoassembly (TNA) could provide efficient intracellular drug delivery in breast tumor cells overexpressing epidermal growth factor (EGF) receptor and thus improve the efficacy and reduce the side effects of docetaxel." "We prepared the novel docetaxel loaded TNAs formed by polyethylene glycol-distearoylphosphatidylethanolamine (PEG-DSPE) and modified with EGF. Compared with nontargeted nanoassemblies (NNAs), TNAs...
Source: Women's Health Weekly (2009-02-05)
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