Women's Health Weekly
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Breast Cancer
Research from A. Carbone and co-researchers in the area of breast cancer described
February 5th, 2009
According to a study from Milan, Italy, "An automated enzyme metallographic silver in situ hybridization method (SISH) has been reported to successfully determine human epidermal growth factor receptor 2 (HER2) gene amplification. We evaluated the staining and interpretative reproducibility of the HER2 SISH assay at five laboratories and compared SISH results with other in situ hybridization (ISH) methods." "The HER2 gene status of 89 breast carcinomas was analyzed in parallel using manual dual-color fluorescence ISH, manual chromogenic ISH, and bright-field automated SISH. A total of 1098 SISH-stained slides were evaluated. For comparison, all specimens were stained by...
Source: Women's Health Weekly (2009-02-05)
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