Women's Health Weekly
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Breast Cancer
Research reports from D. Fagan and co-authors provide new insights into breast cancer
February 5th, 2009
"After the discovery that depriving certain breast tumors of estrogen promoted tumor regression, therapeutic strategies aimed at depriving tumors of this hormone were developed. The tumorigenic properties of estrogen are regulated through the estrogen receptor-alpha (ER), making understanding the mechanisms that activate this receptor highly relevant," scientists writing in the Journal of Mammary Gland Biology and Neoplasia report. "In addition to estrogen activating the ER, other growth factor pathways, such as the insulin-like growth factors (IGFs), can activate the ER. This review will examine the interaction between these two pathways. Estrogen can activate...
Source: Women's Health Weekly (2009-02-05)
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