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Women's Health Weekly

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Breast Cancer



Studies from R. Brosh and co-authors have provided new information about breast cancer



February 5th, 2009

According to recent research from Rehovot, Israel, "Normal cell growth is governed by a complicated biological system, featuring multiple levels of control, often deregulated in cancers. The role of microRNAs (miRNAs) in the control of gene expression is now increasingly appreciated, yet their involvement in controlling cell proliferation is still not well understood."

"Here we investigated the mammalian cell proliferation control network consisting of transcriptional regulators, E2F and p53, their targets and a family of 15 miRNAs. Indicative of their significance, expression of these miRNAs is downregulated in senescent cells and in breast cancers harboring wild-type...


Source: Women's Health Weekly (2009-02-05)

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