Women's Health Weekly
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Cancer
Research on cancer detailed by scientists at Mayo Clinic
February 5th, 2009
According to recent research published in the Journal of Mammary Gland Biology and Neoplasia, "The insulin-like growth factor pathway plays a major role in cancer cell proliferation, survival and resistance to anti-cancer therapies in many human malignancies, including breast cancer. As a key signaling component of IGF system, the IGF-1 receptor is the target of several investigational agents in clinical and pre-clinical development." "This review will focus on the rationale for targeting the IGF-1 receptor and other components of the IGF-1 system. In addition, we will examine the role of IGF-1 signaling in resistance to clinically important breast cancer...
Source: Women's Health Weekly (2009-02-05)
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