Women's Health Weekly
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Breast Cancer
Findings from University of Basel in breast cancer reported
February 12th, 2009
"Products derived from roots of Leuzea carthamoides (Maral root) are being promoted as dietary supplements with anti-aging, adaptogenic and anabolic activity, without much scientific evidence. We investigated the effects of a lipophilic Leuzea root extract and the major phytoecdysteroid, 20-hydroxyecdysone, in human breast adenocarcinoma MCF-7 cells," scientists in Basel, Switzerland report. "Cell proliferation was inhibited by the extract IC50 = 30 mu g/mL) but not by 20-hydroxyecdysone. Genorne-wide expression profiling using Affymetrix HG U133 Plus 2.0 microarrays was carried out to analyse effects at the transcriptional level. 241 genes appeared to be differentially...
Source: Women's Health Weekly (2009-02-12)
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