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Women's Health Weekly

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Breast Cancer



New breast cancer research from M.A. Loizidou and colleagues discussed



February 12th, 2009

According to recent research from Nicosia, Cyprus, "Based studies have reported signifiant associations between specific genetic polymorphisms and breast cancer susceptibility. A number of studies have demonstrated that common variants of genes involved in the DNA repair pathway act as low penetrance breast cancer susceptibility alleles."

"We aimed to investigate the association of single nucleotide polymorphisms (SNPs) in the DNA repair genes XRCC1, XRCC2 and XRCC3 and breast cancer in MASTOS, a population-based case-control study of 1,109 Cypriot women with breast cancer diagnosed between 40 and 70 years and 1,177 age-matched healthy controls. Five coding SNPs were...


Source: Women's Health Weekly (2009-02-12)

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