Women's Health Weekly
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Breast Cancer
New breast cancer study results reported from University of California
February 12th, 2009
"MCF7 cells are an estrogen-responsive human breast cancer cell line that expresses both estrogen receptor (ER) alpha and ER beta. Treatment of MCF7 cells with artemisinin, an antimalarial phytochemical from the sweet wormwood plant, effectively blocked estrogen-stimulated cell cycle progression induced by either 17 beta-estradiol (E-2), an agonist for both ERs, or by propyl pyrazole triol (PPT), a selective ER alpha agonist," scientists in the United States report. "Artemisinin strongly downregulated ER alpha protein and transcripts without altering expression or activity of ER beta. Transfection of MCF7 cells with ER alpha promoter-linked luciferase reporter plasmids...
Source: Women's Health Weekly (2009-02-12)
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