Women's Health Weekly
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Breast Cancer
New findings from Osaka University, Medical Department in the area of breast cancer described
February 12th, 2009
According to recent research from Suita, Japan, "Adiponectin is one of the most important adipocytokines secreted from adipose tissue. In addition to its effects on glucose and fatty acid metabolism, it has been reported that adiponectin has a direct growth-inhibitory effect on breast cancer cells." "However, it still remains to be established how adiponectin affects cell cycle and apoptosis and whether or not its inhibitory effect is mediated through adiponectin receptors. Here, we demonstrated that adiponectin treatment resulted in a significant dose-dependent growth inhibition of both MDA-MB-231 and T47D cells. In both cell lines, the G0/G1 population significantly...
Source: Women's Health Weekly (2009-02-12)
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