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Women's Health Weekly

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Breast Cancer



New research on breast cancer from B. Vancalster and co-authors summarized



February 12th, 2009

" To examine the frequency of axillary lymph node (ALN) invasion of operable breast cancers by their combined oestrogen receptor (ER), progesterone receptor (PR) and HER-2 status. Methods 2227 recently operated cases in one centre were retrieved from the Multidisciplinary Breast Centre database and stratified according to their combined immunohistochemical (IHC) expression of ER/PR/HER-2 status," researchers in Leuven, Belgium report.

"An equivocal HER-2 status was further analysed by Fluorescence in situ Hybridisation (FISH). The following 6 groups were considered: ER-PR-HER-2(-) (NNN; triple negative), ER-PR-HER-2(+) (NNP), ER+PR-HER-2(-) (PNN), ER+PR-HER-2(+) (PNP),...


Source: Women's Health Weekly (2009-02-12)

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