Women's Health Weekly
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Breast Cancer
Research findings from Nanjing Medical University, Medical University Center update understanding of breast cancer
February 12th, 2009
"Fibroblast growth factor receptor 2 (FGFR2) belongs to the FGFR family, which plays an important role in cell growth, invasiveness, motility and angiogenesis. In human breast cancer, expression of FGFR2 is estrogen receptor (ER)-dependent and correlates with a lower rate of apoptosis," scientists writing in the journal Carcinogenesis report. "Recently, whole-genome association studies have identified several single-nucleotide polymorphisms (SNPs) of FGFR2 as novel breast cancer susceptibility loci. In the present study of 1049 breast cancer patients and 1073 cancer-free controls, we assessed whether polymorphisms of FGFR2 are associated with breast cancer risk...
Source: Women's Health Weekly (2009-02-12)
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