Women's Health Weekly
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Breast Cancer
Research in the area of breast cancer reported from Stanford University
February 12th, 2009
" HER2 gene amplification and/or protein overexpression in breast cancer is associated with a poor prognosis and predicts response to anti-HER2 therapy. We examine the natural history of breast cancers in relationship to increased HER2 copy numbers in a large population-based study," investigators in the United States report. "Patients and Methods HER2 status was measured by fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) in approximately 1,400 breast cancer cases with greater than 15 years of follow-up. Protein expression was evaluated with two different commercially-available antibodies. We looked for subgroups of breast cancer with different...
Source: Women's Health Weekly (2009-02-12)
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