Women's Health Weekly
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Breast Cancer
Researchers at University of Palermo target breast cancer
February 12th, 2009
According to recent research published in the journal Breast Cancer Research and Treatment, "Various studies have been published in Italy regarding the different BRCA1 mutations, but only the BRCA1-5083del19 mutation is recurrent and specific to individuals of Italian descent with a founder effect on the Calabrian population. In our previous study, BRCA1-5083del19 mutation carriers were found in four index cases of 106 Sicilian patients selected for familial and/or hereditary breast/ovarian cancers." "The high frequency rate of this mutation identified in the Sicilian population led us to perform haplotype analysis in all family carriers. Five highly polymorphic...
Source: Women's Health Weekly (2009-02-12)
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