Women's Health Weekly
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American Academy of Sleep Medicine
Pregnancy-related hormonal changes linked to increased risk of restless legs syndrome
February 19th, 2009
A study in the Feb. 1 issue of the journal Sleep shows that the elevation in estradiol levels that occurs during pregnancy is more pronounced in pregnant women with restless legs syndrome (RLS) than in controls. During the last trimester of pregnancy, levels of the estrogenic steroid hormone estradiol were 34,211 pg/mL in women with RLS and 25,475 pg/mL in healthy controls. At three months postpartum, estradiol levels had dropped to 30.73 pg/mL in the RLS group and 94.92 pg/mL in controls. Other hormone levels did not differ significantly between the study groups. According to the authors the data strongly suggest that estrogens play an important...
Source: Women's Health Weekly (2009-02-19)
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