Women's Health Weekly
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Breast Cancer
Reports outline breast cancer research from P.L. Boulay and colleagues
February 19th, 2009
According to recent research from Montreal, Canada, "Activation of intracellular signaling pathways by growth factors is one of the major causes of cancer development and progression. Recent studies have demonstrated that monomeric G proteins of the Ras family are key regulators of cell proliferation, migration, and invasion." "Using an invasive breast cancer cell lines, we demonstrate that the ADP-ribosylation factor 1 (ARF1), a small GTPase classically associated with the Golgi, is an important regulator of the biological effects induced by epidermal growth factor. Here, we show that this ARF isoform is activated following epidermal growth factor stimulation and that,...
Source: Women's Health Weekly (2009-02-19)
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