Pelvic Organ Prolapse Genetics
Study findings from University of Hawaii provide new insights into pelvic organ prolapse genetics
Published in Women's Health Weekly, February 19th, 2009
Researchers detail in 'Gene expression profile in pelvic organ prolapse,' new data in pelvic organ prolapse. "It was hypothesized that the processes contributing to pelvic organ prolapse (POP) may be identified by transcriptional profiling of pelvic connective tissue in conjunction with light microscopy. In order to test this, we performed a frequency-matched case-control study of women undergoing hysterectomy for POP and controls," scientists in the United States report.
"Total RNA, extracted from uterosacral and round ligament samples used to generate labeled cRNA, was hybridized to microarrays and analyzed for the expression of 32 878 genes. Significance Analysis of...
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