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Women's Health Weekly

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Breast Cancer



Study findings on breast cancer are outlined in reports from A. Mangia and colleagues



February 19th, 2009

According to recent research from Bari, Italy, "The aim of the study was to evaluate the performance of immunohistochemical MS110 expression in a series of familial and sporadic breast cancer patients. An immunohistochemical study was performed on TMA samples from 93 sporadic and 94 familial breast cancer patients with (7/94) and without BRCA1 germline mutations."

"BRCA1 protein expression level was evaluated using the monoclonal MS110 antibody. Immunohistochemistry, performed on TMA samples, showed positive nuclear staining for BRCA1 in 34 sporadic and 37 familial breast tumours, respectively. All the tumours from patients carrying BRCA1 mutations showed complete loss...


Source: Women's Health Weekly (2009-02-19)

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