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Women's Health Weekly

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Breast Cancer



Reports outline breast cancer study results from T. Cigler et al



February 26th, 2009

"The introduction of modern chemotherapy agents, including the taxanes, has improved the prognosis of women with metastatic breast cancer (MBC). Ultimately, however, inevitable intrinsic or acquired resistance to chemotherapy limits treatment options," investigators in the United States report.

"The epothilones, a novel class of microtubule-stabilizing agents that have incomplete cross-resistance with taxanes and are less susceptible to common mechanisms of resistance, have demonstrated activity in breast cancer. Ixabepilone, the best studied epothilone to date, has been approved for use as a single agent or in combination with capecitabine in anthracycline- and...


Source: Women's Health Weekly (2009-02-26)

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