Women's Health Weekly
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Breast Cancer
Reports summarize breast cancer research from W. Zhou and co-authors
February 26th, 2009
" Not only is the expression of CXCR4 on breast cancers a key determinant of tumor metastasis, CXCL12 exhibiting peak levels of constitutive expression in organs representing the first destinations of cancer metastasis, but is proposed to be also essential for the organ-specific metastatic process. In this study, the expressions of CXCR4 and CXCL12 were investigated using quantitative RT-PCR and immunohistochemistry in samples of 63 primary breast carcinomas and 20 normal breast tissues," scientists in Jinan, People's Republic of China report. "Using methylation-specific PCR, we also analyzed the methylation status of CXCL12. Both up-regulation of CXCR4 and...
Source: Women's Health Weekly (2009-02-26)
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