Women's Health Weekly
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Breast Cancer
Investigators at McGill University target breast cancer
March 5th, 2009
"Cancer cells with stem cell-like properties (cancer stem cells) are believed to drive cancer and are associated with poor prognosis," scientists writing in the Journal of Cell Science report. "Data from mouse models have demonstrated that integrins, the major cellular receptors for extracellular-matrix components, have essential roles both during cancer initiation and progression, and during cell differentiation in normal development. By presenting an overview of the role of integrins in stem-cell biology and in cancer progression, this Commentary aims to present evidence for a role of integrins in the biology of cancer stem cells," wrote S.M. Pontier and...
Source: Women's Health Weekly (2009-03-05)
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