Women's Health Weekly
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Breast Cancer
New breast cancer research from M. Jannuzzo et al outlined
March 5th, 2009
" Luteinizing hormone-releasing hormone (LHRH) agonists (e.g., triptorelin) reduce ovarian estrogen production in premenopausal women with hormone-sensitive breast cancer. Aromatase inhibitors (e.g., exemestane) inhibit extraovarian production of estrogen and may further reduce circulating estrogens when combined with an LHRH agonist," researchers in the United States report. " Healthy premenopausal women were randomized to receive 3.75 mg triptorelin (T) on days 1 and 29 with 25 mg exemestane (EX) or matched placebo once daily for 8 weeks, from day 1 to day 56. The primary objective was to evaluate the effect of T +/- A EX on estradiol (E-2) suppression by comparing...
Source: Women's Health Weekly (2009-03-05)
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