Women's Health Weekly
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Breast Cancer
New breast cancer study findings have been reported by N. Patani and co-researchers
March 5th, 2009
According to a study from London, the United Kingdom, "Osteopontin (OPN) overexpression in breast cancer has been associated with adverse pathological and clinical outcomes. In this study, the OPN expression profiles were examined in a cohort of breast cancer patients." "RNA extraction and reverse transcription were performed on breast carcinomas (n=127) and normal tissues (n=33). Transcript levels were determined using real-time PCR. The OPN-a levels decreased with increasing TNM stage and worse clinical outcome. The OPN-b levels increased with tumour grade and Nottingham Prognostic Index (NPI) stage, were higher in patients who died of breast cancer than in those who...
Source: Women's Health Weekly (2009-03-05)
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