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Angiogenesis

Data from C.B. Pizarro et al provide new insights into angiogenesis

Published in Women's Health Weekly, March 5th, 2009

Research findings, 'Evaluation of angiogenesis in 77 pituitary adenomas using endoglin as a marker,' are discussed in a new report. According to a study from Porto Alegre, Brazil, "Angiogenesis, a fundamental process for the development and growth of a tumor, is less expressive in adenomas than in the normal pituitary tissue. There is controversy about the behavior of angiogenesis as a function of hormonal secretion or other characteristics of pituitary tumors."

"Endoglin (CD105) is a proliferation-associated antigen on endothelial cells, as well as an endothelial progenitor cell marker. We used the anti-endoglin antibody, a glycoprotein expressed in endothelial cells...

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