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Female Infertility Genetics

Researchers from University of Sao Paulo detail findings in female infertility genetics

Published in Women's Health Weekly, March 5th, 2009

Research findings, 'Inactivating mutations of luteinizing hormone beta-subunit or luteinizing hormone receptor cause oligo-amenorrhea and infertility in women,' are discussed in a new report. According to recent research from Sao Paulo, Brazil, "Women harbouring inactivating mutations in luteinizing hormone (LH) beta subunit (LHB) or LH receptor (LHCGR) genes have similar clinical manifestations characterized by female external genitalia, spontaneous breast and pubic hair development at puberty, and normal or late menarche followed by oligo-amenorrhea and infertility. Oestradiol and progesterone levels are normal for the early to midfollicular phase, but do not reach ovulatory or luteal...

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